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Fakultät für Lebenswissenschaften: Lebensmittel, Ernährung und Gesundheit

Lehrstuhl für Molekulare Sportphysiologie – Professor Dr. Frank Suhr

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Publikationen

2023

Athanassios Fragoulis, Mersedeh Tohidnezhad, Yusuke Kubo, Christoph Jan Wruck, Rogerio Bastos Craveiro, Anna Bock, Michael Wolf, Thomas Pufe, Holger Jahr, Frank Suhr: The Contribution of the Nrf2/ARE System to Mechanotransduction in Musculoskeletal and Periodontal Tissues. In: International Journal of Molecular Sciences, 24 (2023). - .
doi:10.3390/ijms24097722

Ana Victoria Rojo‐García, Mathias Vanmunster, Alexander Pacolet, Frank Suhr: Physical inactivity by tail suspension alters markers of metabolism, structure, and autophagy of the mouse heart. In: Physiological Reports, 11 (2023). - .
doi:10.14814/phy2.15574

2022

Ingo Thievessen, Frank Suhr, Silvia Vergarajauregui, Ralph T. Böttcher, Klara Brixius, Georg Rosenberger, Oliver Dewald, Bernd K. Fleischmann, Alexander Ghanem, Marcus Krüger, Felix B. Engel, Ben Fabry, Wilhelm Bloch, Reinhard Fässler: The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load. In: Current Biology, 32 (2022). - S. 3033-3047.e9.
doi:10.1016/j.cub.2022.05.047

Mathias Vanmunster, Ana Victoria Rojo Garcia, Alexander Pacolet, Sebastiaan Dalle, Katrien Koppo, Ilse Jonkers, Rik Lories, Frank Suhr: Mechanosensors control skeletal muscle mass, molecular clocks, and metabolism. In: Cellular and Molecular Life Sciences, 79 (2022). - .
doi:10.1007/s00018-022-04346-7

Bernhard Andresen, Markus de Marees, Thorsten Schiffer, Wilhelm Bloch, Frank Suhr: Skeletal muscle fiber type‐specific expressions of mechanosensors integrin‐linked kinase, talin, and vinculin and their modulation by loading and environmental conditions in humans. In: The FASEB Journal, 36 (2022). - .
doi:10.1096/fj.202101377RR

2021

Frank Suhr, Sarah Knuth, Silvia Achtzehn, Joachim Mester, Markus de Marees: Acute Exhaustive Exercise under Normoxic and Normobaric Hypoxic Conditions Differentially Regulates Angiogenic Biomarkers in Humans. In: Medicina, 57 (2021). - .
doi:10.3390/medicina57070727

Raphael Reuten, Sina Zendehroud, Monica Nicolau, Lutz Fleischhauer, Anu Laitala, Stefanie Kiderlen, Denise Nikodemus, Lena Wullkopf, Sebastian Rune Nielsen, Sarah McNeilly, Carina Prein, Maria Rafaeva, Erwin M. Schoof, Benjamin Furtwängler, Bo T. Porse, Hyobin Kim, Kyoung Jae Won, Stefanie Sudhop, Kamilla Westarp Zornhagen, Frank Suhr, Eleni Maniati, Oliver M. T. Pearce, Manuel Koch, Lene Broeng Oddershede, Tom Van Agtmael, Chris D. Madsen, Alejandro E. Mayorca-Guiliani, Wilhelm Bloch, Roland R. Netz, Hauke Clausen-Schaumann, Janine T. Erler: Basement membrane stiffness determines metastases formation. In: Nature Materials, 20 (2021). - S. 892-903.
doi:10.1038/s41563-020-00894-0

Sebastiaan Dalle, Evelien Van Roie, Charlotte Hiroux, Mathias Vanmunster, Walter Coudyzer, Frank Suhr, Stijn Bogaerts, Ruud Van Thienen, Katrien Koppo: Omega-3 supplementation improves isometric strength but not muscle anabolic and catabolic signaling in response to resistance exercise in healthy older adults. In: The Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 76 (2021). - S. 406-414.
doi:10.1093/gerona/glaa309

2020

Thorsten Gnad, Gemma Navarro, Minna Lahesmaa, Laia Reverte-Salisa, Francesca Copperi, Arnau Cordomi, Jennifer Naumann, Aileen Hochhäuser, Saskia Haufs-Brusberg, Daniela Wenzel, Frank Suhr, Naja Zenius Jespersen, Camilla Scheele, Volodymyr Tsvilovskyy, Christian Brinkmann, Joern Rittweger, Christian Dani, Mathias Kranz, Winnie Deuther-Conrad, Holger K. Eltzschig, Tarja Niemi, Markku Taittonen, Peter Brust, Pirjo Nuutila, Leonardo Pardo, Bernd K. Fleischmann, Matthias Blüher, Rafael Franco, Wilhelm Bloch, Kirsi A. Virtanen, Alexander Pfeifer: Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity. In: Cell Metabolism, 32 (2020). - S. 56-70.
doi:10.1016/j.cmet.2020.06.006

Sebastiaan Dalle, Chiel Poffé, Charlotte Hiroux, Frank Suhr, Louise Deldicque, Katrien Koppo: Ibuprofen does not Impair Skeletal Muscle Regeneration Upon Cardiotoxin-Induced Injury. In: Physiological Research, 69 (2020). - S. 847-859.
doi:10.33549/physiolres.934482

2019

Frank Suhr, Kristina Braun, Mathias Vanmunster, Wilhelm Bloch: Acute Skeletal Muscle Contractions Orchestrate Signaling Mechanisms to Trigger Nuclear NFATc1 Shuttling and Epigenetic Histone Modifications. In: Cellular Physiology and Biochemistry, 52 (2019). - S. 633-652.
doi:10.33594/000000045

Sebastian Mathes, Mathias Vanmunster, Wilhelm Bloch, Frank Suhr: Evidence for skeletal muscle fiber type-specific expressions of mechanosensors. In: Cellular and Molecular Life Sciences, 76 (2019). - S. 2987-3004.
doi:10.1007/s00018-019-03026-3

Frank Suhr: Extracellular matrix, proteases and physical exercise. In: Deutsche Zeitschrift für Sportmedizin, 70 (2019). - S. 97-104.
doi:10.5960/dzsm.2019.367

Raja Ghazanfar Ali Sahito, Xiaowu Sheng, Martina Maass, Nelly Mikhael, Sarkawt Hamad, Carlos O. Heras-Bautista, Daniel Derichsweiler, Dimitry Spitkovsky, Frank Suhr, Markus Khalil, Konrad Brockmeier, Marcel Halbach, Tomo Saric, Jürgen Hescheler, Benjamin Krausgrill, Kurt Pfannkuche: In vitro grown micro-tissues for cardiac cell replacement therapy in vivo. In: Cellular Physiology and Biochemistry, 52 (2019). - S. 1309-1324.
doi:10.33594/000000092

2017

Jessica Pingel, Frank Suhr: Are mechanically sensitive regulators involved in the function and (patho)physiology of cerebral palsy-related contractures?. In: Journal of Muscle Research and Cell Motility, 38 (2017). - S. 317-330.
doi:10.1007/s10974-017-9489-1

2016

Thijs Maria Anne Ackermans, Gaspar Epro, Christopher McCrum, Kai Daniel Oberländer, Frank Suhr, Maarten Robert Drost, Kenneth Meijer, Kiros Karamanidis: Aging and the effects of a half marathon on Achilles tendon force–elongation relationship. In: European Journal of Applied Physiology, 116 (2016). - S. 2281-2292.
doi:10.1007/s00421-016-3482-z

Sebastian Gehlert, Franz Josef Klinz, Lena Willkomm, Thorsten Schiffer, Frank Suhr, Wilhelm Bloch: Intense Resistance Exercise Promotes the Acute and Transient Nuclear Translocation of Small Ubiquitin-Related Modifier (SUMO)-1 in Human Myofibres. In: International Journal of Molecular Sciences, 17 (2016). - .
doi:10.3390/ijms17050646

L. Greiwe, M. Vinck, Frank Suhr: The muscle contraction mode determines lymphangiogenesis differentially in rat skeletal and cardiac muscles by modifying local lymphatic extracellular matrix microenvironments. In: Acta Physiologica, 217 (2016). - S. 61-79.
doi:10.1111/apha.12633

Marijke Grau, Alexander Lauten, Steffen Hoeppener, Bjoern Goebel, Julian Brenig, Christian Jung, Wilhelm Bloch, Frank Suhr: Regulation of red blood cell deformability is independent of red blood cell-nitric oxide synthase under hypoxia. In: Clinical Hemorheology and Microcirculation, 63 (2016). - S. 199-215.
doi:10.3233/CH-162044

2015

Sebastian Gehlert, Wilhelm Bloch, Frank Suhr: Ca²⁺-dependent regulations and signaling in skeletal muscle : from electro-mechanical Coupling to Adaptation. In: International Journal of Molecular Sciences, 16 (2015). - S. 1066-1095.
doi:10.3390/ijms16011066

Marijke Grau, Petra Friederichs, Sebastian Krehan, Christina Koliamitra, Frank Suhr, Wilhelm Bloch: Decrease in red blood cell deformability is associated with a reduction in RBC-NOS activation during storage. In: Clinical Hemorheology and Microcirculation, 60 (2015). - S. 215-229.
doi:10.3233/CH-141850

Frank Suhr: Detection of fusion events in mammalian skeletal muscle. In: Kurt Pfannkuche (Hrsg.): Cell Fusion : Overviews and Methods. 2. Auflage. - New York : Humana Press, 2015. - S. 115-129.
doi:10.1007/978-1-4939-2703-6_8

Sebastian Gehlert, Frank Suhr, Katrin Gutsche, Lena Willkomm, Julia Kern, Daniel Jacko, Axel Knicker, Thorsten Schiffer, Henning Wackerhage, Wilhelm Bloch: High force development augments skeletal muscle signalling in resistance exercise modes equalized for time under tension. In: Pflügers Archiv : European Journal of Physiology, 467 (2015). - S. 1343-1356.
doi:10.1007/s00424-014-1579-y

Marijke Grau, Anaïs Mozar, Keyne Charlot, Yann Lamarre, Linda Weyel, Frank Suhr, Bianca Collins, Stéphane Jumet, Marie-Dominique Hardy-Dessources, Marc Romana, Nathalie Lemonne, Maryse Etienne-Julan, Sophie Antoine-Jonville, Wilhelm Bloch, Philippe Connes: High red blood cell nitric oxide synthase activation is not associated with improved vascular function and red blood cell deformability in sickle cell anaemia. In: British Journal of Haematology, 168 (2015). - S. 728-736.
doi:10.1111/bjh.13185

Sebastian Frese, Matthias Ruebner, Frank Suhr, Thierry M. Konou, Kim A. Tappe, Marco Toigo, Hans H. Jung, Christine Henke, Ruth Steigleder, Pamela L. Strissel, Hanna Huebner, Matthias W. Beckmann, Piet van der Keylen, Benedikt Schoser, Thorsten Schiffer, Laura Frese, Wilhelm Bloch, Reiner Strick: Long-Term Endurance Exercise in Humans Stimulates Cell Fusion of Myoblasts along with Fusogenic Endogenous Retroviral Genes In Vivo. In: PLoS One, 10 (2015). - .
doi:10.1371/journal.pone.0132099

Anaïs Mozar, Marijke Grau, Yann Lamarre, Linda Weyel, Frank Suhr, Bianca Collins, Marie-Dominique Hardy-Dessources, Marc Romana, Nathalie Lemonne, Maryse Etienne-Julan, Wilhelm Bloch, Philippe Connes: Red blood cell nitric oxide synthase activation is increased in patients with sickle cell hemoglobin C disease. In: American Journal of Hematology, 90 (2015). - S. E30-E32.
doi:10.1002/ajh.23894

2014

Anna E. Müller, Matthias Kreiner, Sebastian Kötter, Philipp Lassak, Wilhelm Bloch, Frank Suhr, Martina Krüger: Acute exercise modifies titin phosphorylation and increases cardiac myofilament stiffness. In: Frontiers in Physiology, 5 (2014). - .
doi:10.3389/fphys.2014.00449

Birgit Bölck, Marwa Ibrahim, Dirk Steinritz, Christian Morguet, Sandra Dühr, Frank Suhr, Juxian Lu-Hesselmann, Wilhelm Bloch: Detection of key enzymes, free radical reaction products and activated signaling molecules as biomarkers of cell damage induced by benzo[a]pyrene in human keratinocytes. In: Toxicology in Vitro, 28 (2014). - S. 875-884.
doi:10.1016/j.tiv.2014.03.010

Wael A. Attia, Osama M. Abd El Aziz, Dimitry Spitkovsky, John A. Gaspar, Peter Dröge, Frank Suhr, Davood Sabour, Johannes Winkler, Kesavan Meganathan, Smita Jagtap, Markus Khalil, Jürgen Hescheler, Konrad Brockmeier, Agapios Sachinidis, Kurt Pfannkuche: Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies. In: Stem Cell Reviews and Reports, 10 (2014). - S. 1-15.
doi:10.1007/s12015-013-9472-1

Alexander Lauten, Alexandra Gerhard-Garcia, Frank Suhr, Juergen H. Fischer, Hans R. Figulla, Wilhelm Bloch: Impact of ischemia-reperfusion on extracellular matrix processing and structure of the basement membrane of the heart. In: PLoS One, 9 (2014). - .
doi:10.1371/journal.pone.0092833

Lena Willkomm, Sarah Schubert, Raphael Jung, Manuela Elsen, Julika Borde, Sebastian Gehlert, Frank Suhr, Wilhelm Bloch: Lactate regulates myogenesis in C2C12 myoblasts in vitro. In: Stem Cell Research, 12 (2014). - S. 742-753.
doi:10.1016/j.scr.2014.03.004

2013

Frank Suhr, Yvonne Delhasse, Gerd Bungartz, Annette Schmidt, Kurt Pfannkuche, Wilhelm Bloch: Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells. In: Stem Cell Research, 11 (2013). - S. 951-964.
doi:10.1016/j.scr.2013.05.010

Marijke Grau, Sebastian Pauly, Jamal Ali, Katja Walpurgis, Mario Thevis, Wilhelm Bloch, Frank Suhr: RBC-NOS-dependent S-nitrosylation of cytoskeletal proteins improves RBC deformability. In: PLoS One, 8 (2013). - .
doi:10.1371/journal.pone.0056759

Frank Suhr, Sebastian Gehlert, Marijke Grau, Wilhelm Bloch: Skeletal Muscle Function during Exercise : Fine-Tuning of Diverse Subsystems by Nitric Oxide. In: International Journal of Molecular Sciences, 14 (2013). - S. 7109-7139.
doi:10.3390/ijms14047109

Åsa Beijer, André Rosenberger, Birgit Bölck, Frank Suhr, Jörn Rittweger, Wilhelm Bloch: Whole-body vibrations do not elevate the angiogenic stimulus when applied during resistance exercise. In: PLoS One, 8 (2013). - S. e80143.
doi:10.1371/journal.pone.0080143

2012

Frank Suhr, Wilhelm Bloch: Endothelial cell apoptosis : A new focal adhesion makes the difference. In: Circulation Research, 111 (2012). - S. 1488-1490.
doi:10.1161/CIRCRESAHA.112.278713

Sebastian Gehlert, Gerd Bungartz, Lena Willkomm, Yüksel Korkmaz, Kurt Pfannkuche, Thorsten Schiffer, Wilhelm Bloch, Frank Suhr: Intense resistance exercise induces early and transient increases in ryanodine receptor 1 phosphorylation in human skeletal muscle. In: PLoS One, 7 (2012). - .
doi:10.1371/journal.pone.0049326

Frank Suhr, Julian Brenig, Rebecca Müller, Hilke Behrens, Wilhelm Bloch, Marijke Grau: Moderate exercise promotes human RBC-NOS activity, NO production and deformability through Akt kinase pathway. In: PLoS One, 7 (2012). - .
doi:10.1371/journal.pone.0045982

Wilhelm Bloch, Frank Suhr, P. Zimmer: Molekulare Mechanismen der Herz- und Gefäßanpassung durch Sport : Einfluss von Epigenetik, Mechanotransduktion und freien Radikalen = Molecular mechanisms of exercise-induced cardiovascular adaptations : Influence of epigenetics, mechanotransduction and free radicals. In: Herz, 37 (2012). - S. 508-515.
doi:10.1007/s00059-012-3637-6

2010

Jiaoya Xi, Markus Khalil, Nava Shishechian, Tobias Hannes, Kurt Pfannkuche, Huamin Liang, Azra Fatima, Moritz Haustein, Frank Suhr, Wilhelm Bloch, Michael Reppel, Tomo Šarić, Marius Wernig, Rudolf Jänisch, Konrad Brockmeier, Jürgen Hescheler, Frank Pillekamp: Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells. In: The FASEB Journal, 24 (2010). - S. 2739-2751.
doi:10.1096/fj.09-145177

Philippe Connes, Frank Suhr, Cyril Martin, Sehyun Shin, Emeline Aufradet, Sub Sunoo, Klara Brixius, Eric Raynaud de Mauverger, Marc Romana, Laurent Messonnier, Joonku Kang, Emmanuelle Varlet-Marie, Leonard Feasson, Marie-Dominique Hardy-Dessources, Wilhelm Bloch, Jean-Frederic Brun: New fundamental and applied mechanisms in exercise hemorheology. In: Clinical Hemorheology and Microcirculation, 45 (2010). - S. 131-141.
doi:10.3233/CH-2010-1291

2009

Frank Suhr, Klara Brixius, Wilhelm Bloch: Angiogenic and vascular modulation by extracellular matrix cleavage products. In: Current Pharmaceutical Design, 15 (2009). - S. 389-410.
doi:10.2174/138161209787315756

Frank Suhr, Stefan Porten, Tim Hertrich, Klara Brixius, Annette Schmidt, Petra Platen, Wilhelm Bloch: Intensive exercise induces changes of endothelial nitric oxide synthase pattern in human erythrocytes. In: Nitric Oxide, 20 (2009). - S. 95-103.
doi:10.1016/j.niox.2008.10.004

Frank Suhr, C. Rosenwick, A. Vassiliadis, Wilhelm Bloch, Klara Brixius: Regulation of extracellular matrix compounds involved in angiogenic processes in short- and long-track elite runners. In: Scandinavian Journal of Medicine & Science in Sports, 20 (2009). - S. 441-448.
doi:10.1111/j.1600-0838.2009.00960.x

2007

Frank Suhr, Klara Brixius, Markus de Marées, Birgit Bölck, Heinz Kleinöder, Silvia Achtzehn, Wilhelm Bloch, Joachim Mester: Effects of short-term vibration and hypoxia during high-intensity cycling exercise on circulating levels of angiogenic regulators in humans. In: Journal of Applied Physiology, 103 (2007). - S. 474-483.
doi:10.1152/japplphysiol.01160.2006

Verantwortlich für die Redaktion: Univ.Prof.Dr. Frank Suhr

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